Testosterone Replacement Therapy: Potential Side Effects List

Testosterone Replacement Therapy: Potential Side Effects List

Below is list of potential testosterone replacement therapy side effects. When reading the testosterone therapy side effects, please understand that the list has not been comprised to create fear or apprehension about participating in testosterone replacement therapy (TRT).

This list has been made to educate patients of TRT about what could possibly happen in certain situations. This way, knowing the health risks of testosterone therapy will not create surprise if something out of the ordinary occurs during therapy. A patient will understand that the side effect was a potential risk and he or she will know how to handle it with ease, confidence and calmness.

  • Acne
  • Rash
  • Hives
  • Oily skin
  • Redness, itching or irritation at injection site
  • Infection at injection site
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Indigestion
  • Trouble breathing
  • Heart palpitations
  • Pain in chest
  • Pressure in chest
  • Dark colored or blood in urine or stool
  • Blood clots
  • Heart attack or stroke
  • Excessive hunger or thirst
  • Dry mouth
  • Ulcers in mouth or on gums
  • Swelling of hands, feet, ankles, mouth, tongue or throat
  • Bad breath
  • Fruity smell to breath
  • Body, joint or muscle pain
  • Fluid retention
  • Difficulty sleeping
  • Depression or anxiety
  • Irritability, agitation or mood swings
  • Difficulty concentrating or focusing
  • Difficulty with memory
  • Trembling, numbness or tingling
  • Loss of sexual desire or sexual libido
  • Erectile dysfunction
  • Shrinking testicles
  • Enlargement of breasts in men
  • Hot flashes
  • Night sweats

Above is a comprehensive list of the possible side effects testosterone replacement therapy. There may be other issues that can occur that we have not listed. For anything that seems out of the ordinary that occurs with TRT, patients are encouraged to seek help.

Never leave a negative side effect unattended. A problem caused from TRT could get worse when it could have been stopped with help from your doctor. 

What Do Health Experts Say About Testosterone Therapy Risks

What Do Health Experts Say About Testosterone Therapy Risks

Professionals in the medical field of endocrinology weigh in on how they feel about testosterone therapy risks. Experts say that prescribing the exact amount of needed testosterone and not anymore is vital to minimize risks for negative side effects to occur. In other words, the lowest dosage possible is best. In addition, it is vital to have a full medical exam and medical history to be analyzed before a prescription is written.

The most expert TRT doctors will make sure that they are very careful when working with all men, but especially those who have already existing high levels of hematocrit. Men with a red blood disorder or those with a chronic obstructive pulmonary disease may have higher testosterone replacement therapy risks than others without these medical conditions, according to medical sources.

A research article that reviewed many TRT studies was written and published in the New England Journal of Medicine. The conclusion of all the research did not see any severe blood clots or strokes found as a TRT side effect. However, the article did say that the risk does exist.

Doctors also need to be very careful prescribing testosterone medication to those with other issues such as problems with liver or kidney functioning. This should be disclosed in a patient’s medical history form. Why? One of the side effects of testosterone therapy can be fluid retention which is dangerous for those with liver or kidney disease.

In conclusion, the best doctors of testosterone replacement therapy do a thorough analysis of all patient’s medical information for two reasons. (1) To make sure that the person is a good candidate for TRT and (2) To make sure to write the most accurate prescription for the best benefits and to avoid any risks of testosterone replacement therapy as best as possible.

The Most Common And Rare Effects Of Testosterone Therapy

What are the side effects of testosterone replacement therapy that are considered to be the most common and the most rare?

More Common Negative Effects

  • Acne
  • Oily skin
  • Redness at injection site
  • Nausea
  • Vomiting
  • Indigestion
  • Diarrhea
  • Constipation
  • Depression, anxiety, irritability or agitation
  • Shrinking testicles
  • Loss of sexual desire
  • Erectile dysfunction
  • Body, joint of muscle pain

More Rare Negative Effects

  • Fluid retention
  • Heart failure
  • Chest pressure or pain
  • Stroke
  • Problems with kidneys or the liver
  • Sleep apnea
  • Breast enlargement in men (gynecomastia)
  • Difficulty breathing
  • Heart palpitations

It is difficult to say which negative side effects will be more or less common from TRT because all people have varying body chemistry. However, research has found that if negative side effects from testosterone therapy do occur, the above list can be considered accurate.

How To Avoid Negative Effects From Testosterone Therapy

There are several ways to avoid negative effects from testosterone therapy:

  1. The TRT clinic should offer a first free consultation via phone to answer all patient questions regarding TRT, the benefits and possible side effects of testosterone therapy
  2. Only use a testosterone replacement therapy clinic that is well known and reputable
  3. Make sure that your TRT clinic only works with licensed doctors
  4. The clinic must require blood testing, a medical exam to be conducted and a medical history form to be filled out from their website
  5. The doctor must fully analyze all medical information, diagnose the patient (if appropriate) with low T and write a detailed, individualized treatment plan and prescription for the patient
  6. The physician must medically supervise the patient throughout therapy

For more information about testosterone therapy side effects and anything else you might need to know about TRT, please reach out to us. You can fill out our online contact form for the quickest way to speak to one of our expert clinical advisors.

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